Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037119 | 0.81 | HTR2A (0.68) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL30880314 | 0.81 | HTR2A (0.56) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL29593238 | 0.79 | HTR2A (0.63) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL25189373 | 0.79 | HTR2A (0.65) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL7519622 | 0.78 | ATM (0.54) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL14599732 | 0.78 | HTR2A (0.70) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL19432446 | 0.78 | HTR2A (0.67) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL18975354 | 0.78 | HTR2A (0.67) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL18976031 | 0.77 | HTR2A (0.58) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL5827968 | 0.77 | HTR2A (0.80) | HTR2AALDH1A1MAPK1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114272389-B | Eribulin-based antibody-drug conjugates and methods of use | 卫材研究发展管理有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-108883198-B | Eribulin-based antibody-drug conjugates and methods of use | 卫材研究发展管理有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114272389-A | Eribulin-based antibody-drug conjugates and methods of use | 卫材研究发展管理有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-114191428-A | Eribulin-based antibody-drug conjugates and methods of use | 卫材研究发展管理有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114191563-A | Eribulin-based antibody-drug conjugates and methods of use | 卫材研究发展管理有限公司 | 2022-03-18 | — | — | CN | disclosed |