Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28727749 | 0.71 | — | — | |
| SCHEMBL938514 | 0.67 | — | — | |
| SCHEMBL8852498 | 0.63 | — | — | |
| SCHEMBL28706389 | 0.59 | — | — | |
| SCHEMBL21961913 | 0.53 | — | — | |
| SCHEMBL21785 | 0.51 | — | — | |
| SCHEMBL22551346 | 0.51 | — | — | |
| SCHEMBL21602990 | 0.49 | — | — | |
| SCHEMBL4964578 | 0.49 | — | — | |
| SCHEMBL9486013 | 0.49 | FFAR3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163394-A | Chloromethyl-containing isoxazoline derivatives and use thereof | 宁夏苏融达化工有限公司 | 2022-03-11 | — | — | CN | disclosed |