SCHEMBL287136

SCHEMBL287136

NCCCCC(NCc1ccccc1Cl)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.54
TLR2 O60603 2/20 0.48
MMP2 P08253 2/20 0.48
MMP9 P14780 2/20 0.48
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CASR P41180 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MMP8 P22894 1/20 0.43
MMP12 P39900 1/20 0.43
MMP14 P50281 1/20 0.43
NQO1 P15559 1/20 0.43
LMNA P02545 1/20 0.43
PYGL P06737 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287135 1.00 FOLH1 (0.54) FOLH1TLR2MMP2MMP9NPC1
SCHEMBL29982685 0.85 TLR2 (0.49) FOLH1TLR2MMP2MMP9NQO1
SCHEMBL29022050 0.85 TLR2 (0.49) FOLH1TLR2MMP2MMP9NQO1
SCHEMBL10341750 0.84 FOLH1 (0.55) FOLH1MMP2MMP9PYGL
SCHEMBL10341754 0.84 FOLH1 (0.55) FOLH1MMP2MMP9PYGL
SCHEMBL4600134 0.83 FOLH1 (0.59) FOLH1MMP2MMP9NPC1RAB9A
SCHEMBL4600125 0.83 FOLH1 (0.59) FOLH1MMP2MMP9NPC1RAB9A
SCHEMBL3650068 0.81 TLR2 (0.67) FOLH1TLR2MMP2MMP9
SCHEMBL1976380 0.81 TLR2 (0.67) FOLH1TLR2MMP2MMP9
SCHEMBL28217516 0.81 TLR2 (0.62) FOLH1TLR2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102428371-B Peptide ligands of somatostatin receptors BCN PEPTIDES, S.A. (ES) 2015-08-12 CN disclosed
US-8946154-B2 Peptide ligands of somatostatin receptors BCN PEPTIDES, S.A. (ES) 2015-02-03 US disclosed
US-20120122781-A1 PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS BCN PEPTIDES, S.A. (ES) 2012-05-17 US disclosed
CN-102428371-A Peptide ligands of somatostatin receptors BCN PEPTIDES SA 2012-04-25 CN disclosed
EP-2427775-A1 PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS BCN Peptides, S.A. (ES) 2012-03-14 EP disclosed
WO-2010128098-A1 PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS BCN PEPTIDES, S.A. (ES) 2010-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122781-A1 PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS SSTR3, SSTR4, SSTR5 FOLH1 798/4885TLR2 1642/4885MMP2 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.