SCHEMBL28716445

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

nearest known ligand 0.85

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	16/20	0.79

▸	GCGR	P47871	9/20	0.79

▸	GIPR	P48546	6/20	0.78

▸	KEAP1	Q14145	1/20	0.71

▸	CALCR	P30988	1/20	0.69

▸	CCKBR	P32239	2/20	0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29357267	0.98	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
Exenatide SCHEMBL20509814	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
SCHEMBL29429437	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
Exenatide SCHEMBL29710890	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
SCHEMBL31072728	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
Exenatide SCHEMBL29827241	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
Exenatide SCHEMBL14634818	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
SCHEMBL29922593	0.97	GLP1R (0.77)	GLP1RGCGRGIPRKEAP1CALCR
Exenatide SCHEMBL28323280	0.97	GLP1R (0.81)	GLP1RGCGRGIPRKEAP1CCKBR
Exenatide SCHEMBL28285812	0.97	GLP1R (0.82)	GLP1RGCGRGIPRKEAP1CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114269369-A	Exenatide compositions for pulmonary administration and uses thereof	艾伊拉米治疗有限公司	2022-04-01	—	—	CN	disclosed