Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | ICMT | O60725 | 13/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 3/20 | 0.51 |
| ▸ | FNTB | P49356 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871986 | 1.00 | MAPT (0.62) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL19859350 | 0.90 | MAPT (0.77) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL1814594 | 0.90 | MAPT (0.77) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL1814592 | 0.90 | MAPT (0.77) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL14328063 | 0.90 | MAPT (0.77) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL18298108 | 0.90 | MAPT (0.77) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL18739961 | 0.90 | MAPT (0.77) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL21045073 | 0.88 | MAPT (0.76) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL2821553 | 0.88 | MAPT (0.76) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL2821551 | 0.88 | MAPT (0.76) | MAPTALDH1A1ICMTMEN1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745589-B1 | Antibodies and unnatural substrates of prenylation enzymes for use in detecting and isolating prenylated proteins | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-06-29 | — | — | US | disclosed |