Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18763395 | 1.00 | GAA (0.43) | GAAKMT2AL3MBTL1TP53NAAA | |
| SCHEMBL18763112 | 0.90 | KMT2A (0.43) | GAAKMT2AL3MBTL1NFKB1NFKB2 | |
| SCHEMBL18763097 | 0.90 | KMT2A (0.43) | GAAKMT2AL3MBTL1NFKB1NFKB2 | |
| SCHEMBL17224584 | 0.90 | KMT2A (0.55) | GAAKMT2AL3MBTL1NPY1RALDH1A1 | |
| SCHEMBL18740602 | 0.84 | KMT2A (0.43) | KMT2AL3MBTL1TP53MEN1SMN1; SMN2 | |
| SCHEMBL2010969 | 0.80 | GAA (0.51) | GAAKMT2AL3MBTL1NFKB1NFKB2 | |
| SCHEMBL2010967 | 0.80 | GAA (0.51) | GAAKMT2AL3MBTL1NFKB1NFKB2 | |
| SCHEMBL2011317 | 0.78 | GAA (0.49) | GAAKMT2AL3MBTL1NFKB1NFKB2 | |
| SCHEMBL2011320 | 0.78 | GAA (0.49) | GAAKMT2AL3MBTL1NFKB1NFKB2 | |
| SCHEMBL1543088 | 0.78 | TP53 (0.50) | KMT2AL3MBTL1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368101-B | Selective NR2B antagonists | 百时美施贵宝公司 | 2022-03-15 | — | — | CN | disclosed |