Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.79 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.43 |
| ▸ | DUT | P33316 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28737105 | 1.00 | CYP3A4 (0.79) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL28737102 | 1.00 | CYP3A4 (0.79) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL28745229 | 1.00 | CYP3A4 (0.79) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL28745230 | 1.00 | CYP3A4 (0.79) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL15728982 | 0.95 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL2525660 | 0.95 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL19283470 | 0.95 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL3755012 | 0.95 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL2525665 | 0.95 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY4POLA1 | |
| SCHEMBL15876420 | 0.95 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY4POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218936-B | Isomer of biphenyl nucleoside phosphoramidate compound and amorphous compound thereof | 南京圣和药业股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108218938-B | Crystal form of biphenyl nucleoside phosphoramidate compound, preparation method and application thereof | 南京圣和药业股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108218937-B | Optical isomer of nucleoside phosphoramidate compound and application thereof | 南京圣和药业股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108218939-B | Novel crystal form of biphenyl nucleoside phosphoramidate compound and preparation method thereof | 南京汇诚制药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-109503686-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-108546277-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-108314697-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |