SCHEMBL28720346 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BRD4	O60885	19/20	0.58

▸	EP300	Q09472	2/20	0.47

▸	CYP17A1	P05093	1/20	0.45

▸	BRD2	P25440	1/20	0.45

▸	ADORA2B	P29275	1/20	0.45

▸	TSPO	P30536	1/20	0.45

▸	BRD3	Q15059	1/20	0.45

▸	BRDT	Q58F21	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29548873	1.00	BRD4 (0.58)	BRD4EP300CYP17A1BRD2ADORA2B
SCHEMBL29548942	0.90	BRD4 (0.65)	BRD4EP300BRD2ADORA2BTSPO
SCHEMBL28720367	0.90	BRD4 (0.65)	BRD4EP300BRD2ADORA2BTSPO
SCHEMBL29548701	0.87	BRD4 (0.57)	BRD4EP300BRD2ADORA2BTSPO
SCHEMBL28718892	0.87	BRD4 (0.57)	BRD4EP300BRD2ADORA2BTSPO
SCHEMBL29548631	0.86	BRD4 (0.56)	BRD4EP300BRD2ADORA2BTSPO
SCHEMBL29548880	0.85	BRD4 (0.59)	BRD4EP300BRD2ADORA2BTSPO
SCHEMBL28720340	0.85	BRD4 (0.59)	BRD4EP300BRD2ADORA2BTSPO
SCHEMBL29548625	0.85	BRD4 (0.50)	BRD4EP300BRD2BRD3BRDT
SCHEMBL28718931	0.85	BRD4 (0.50)	BRD4EP300BRD2BRD3BRDT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110041253-B	Pyridine N-oxide derivative and preparation method and application thereof	上海翰森生物医药科技有限公司	2022-03-29	—	—	CN	disclosed