Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22721391 | 0.86 | GSK3B (0.56) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL28543600 | 0.85 | HIF1A (0.56) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL20543169 | 0.85 | GSK3B (0.55) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3380393 | 0.84 | GSK3B (0.57) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL307839 | 0.84 | GSK3B (0.54) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL28810975 | 0.82 | HIF1A (0.57) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL30419781 | 0.81 | NPC1 (0.58) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL28002211 | 0.81 | GSK3B (0.51) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL18910294 | 0.81 | GSK3B (0.51) | GSK3BHIF1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL966444 | 0.81 | GSK3B (0.51) | GSK3BHIF1AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315760-A | Preparation method and application of 2-chloro-1- (4-morpholinylphenyl) -1-butanone | 内蒙古久日新材料有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114315760-A | Preparation method and application of 2-chloro-1- (4-morpholinylphenyl) -1-butanone | 内蒙古久日新材料有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114315760-A | Preparation method and application of 2-chloro-1- (4-morpholinylphenyl) -1-butanone | 内蒙古久日新材料有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114315760-A | Preparation method and application of 2-chloro-1- (4-morpholinylphenyl) -1-butanone | 内蒙古久日新材料有限公司 | 2022-04-12 | — | — | CN | disclosed |