Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9131250 | 0.82 | — | — | |
| SCHEMBL10388761 | 0.82 | — | — | |
| Iodide SCHEMBL60665 | 0.82 | — | — | |
| SCHEMBL11631041 | 0.82 | — | — | |
| SCHEMBL11633001 | 0.82 | — | — | |
| SCHEMBL11629843 | 0.82 | — | — | |
| Iodide SCHEMBL7922251 | 0.82 | — | — | |
| SCHEMBL3963314 | 0.82 | — | — | |
| Iodide SCHEMBL21530823 | 0.82 | — | — | |
| Iodide SCHEMBL9632840 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476223-B2 | REACTING N-(3-(3-(DIMETHYLAMINE)-OXO-2-PROPENYL)PHENYL) ACETAMIDE WITH ETHYL IODIDE IN THE PRESENCE OF SODIUM HYDRIDE IN DIMETHYLFORMAMIDE; DILUTING (N-(3-(3-(DIMETHYLAMINE)-1-OXO-2-PROPENYL)ACETAMIDE | GADOR S. A. (AR) | 2002-11-05 | — | — | US | claimed |
| US-20020072605-A1 | Method for obtaining N-[3(3-cyano-pyrazole[1,5-a]pyrimidine-7-yl)phenyl]-N-ethyl-acetamide | GADOR S.A. (AR) | 2002-06-13 | — | — | US | claimed |
| CN-111819184-B | Synthetic oligosaccharide derivatives as vaccine against bordetella pertussis | 芬兰疫苗研究所 | 2024-01-12 | — | — | CN | disclosed |
| CN-111819184-A | Synthetic oligosaccharide derivatives as vaccines against bordetella pertussis | 芬兰疫苗研究所 | 2020-10-23 | — | — | CN | disclosed |
| US-RE47475-E1 | Selective agents for pain suppression | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| CN-103483236-B | Prepare method and the intermediate of 5-biphenyl-4-yl-2-methylpentanoic acid derivatives | 诺华股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| US-8835424-B2 | Selective agents for pain suppression | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-16 | — | — | US | disclosed |
| CN-103483236-A | Process and intermediates for the preparation of 5-biphenyl-4-yl-2-methylpentan0ic acid derivatives | NOVARTIS AG | 2014-01-01 | — | — | CN | disclosed |
| CN-101952249-B | Process and intermediates for the preparation of 5-biphenyl-4-yl-2-methylpentanoic acid derivatives | NOVARTIS AG | 2013-10-16 | — | — | CN | disclosed |
| CN-101952249-A | Process and intermediates for the preparation of 5-biphenyl-4-yl-2-methylpentanoic acid derivatives | NOVARTIS AG | 2011-01-19 | — | — | CN | disclosed |
| US-20100317619-A1 | Selective Agents for Pain Suppression | COOK JAMES | 2010-12-16 | — | — | US | disclosed |
| EP-1294702-A1 | BENZODIAZEPINE DERIVATIVES AS APP MODULATORS | MERCK SHARP & DOHME LTD. (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001090084-A1 | BENZODIAZEPINE DERIVATIVES AS APP MODULATORS | MERCK SHARP & DOHME LIMITED (GB) | 2001-11-29 | — | — | WO | disclosed |
| US-5952321-A | Substituted azetidinones as anti-inflammatory and antidegenerative agents | MERCK & CO., INC. (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0666846-A4 | — | — | 1995-09-20 | — | — | EP | disclosed |
| EP-0666846-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO. INC. (US) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994010143-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1994-05-11 | — | — | WO | disclosed |
| WO-1992013451-A1 | IMIDAZOLE PESTICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-08-20 | — | — | WO | disclosed |
| US-5081313-A | PROCESS FOR THE PREPARATION OF 2,3-DIALKOXYPROPANALS | BASF AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |
| US-4186142-A | Cyclization substrates and 6α-substituted 19-norsteroid derivatives | AKZONA INCORPORATED (US) | 1980-01-29 | — | — | US | disclosed |