Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581741 | 1.00 | KLKB1 (0.44) | KLKB1HDAC8LMNANPSR1 | |
| SCHEMBL28721706 | 0.90 | KLKB1 (0.42) | KLKB1HDAC8 | |
| SCHEMBL28938008 | 0.88 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL29580618 | 0.88 | KLKB1 (0.54) | KLKB1LMNANPSR1 | |
| SCHEMBL28721899 | 0.88 | KLKB1 (0.54) | KLKB1LMNANPSR1 | |
| SCHEMBL29580657 | 0.88 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL24570385 | 0.87 | KLKB1 (0.43) | KLKB1HDAC8LMNANPSR1 | |
| SCHEMBL20584585 | 0.87 | KLKB1 (0.43) | KLKB1HDAC8LMNANPSR1 | |
| SCHEMBL29638954 | 0.87 | KLKB1 (0.43) | KLKB1HDAC8LMNANPSR1 | |
| SCHEMBL28724191 | 0.87 | KLKB1 (0.46) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289893-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-04-12 | — | — | CN | disclosed |