Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446591 | 1.00 | KLKB1 (0.54) | KLKB1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL22686018 | 1.00 | KLKB1 (0.54) | KLKB1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL29580636 | 1.00 | KLKB1 (0.54) | KLKB1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL28721887 | 0.92 | KLKB1 (0.61) | KLKB1MEN1KMT2A | |
| SCHEMBL21726675 | 0.92 | KLKB1 (0.61) | KLKB1MEN1KMT2A | |
| SCHEMBL20446637 | 0.92 | KLKB1 (0.61) | KLKB1MEN1KMT2A | |
| SCHEMBL29581006 | 0.92 | KLKB1 (0.61) | KLKB1MEN1KMT2A | |
| SCHEMBL22683222 | 0.91 | KLKB1 (0.50) | KLKB1MEN1KMT2A | |
| SCHEMBL21700374 | 0.91 | KLKB1 (0.50) | KLKB1MEN1KMT2A | |
| SCHEMBL31456788 | 0.91 | KLKB1 (0.50) | KLKB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289893-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-04-12 | — | — | CN | disclosed |