Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075073 | 0.83 | TRPV1 (0.35) | PKMPKLRMALT1LMNAHPGD | |
| SCHEMBL8948819 | 0.80 | HTR1D (0.34) | PKMPKLRMALT1LMNAHPGD | |
| SCHEMBL15075059 | 0.76 | HTR2C (0.47) | PKMPKLRMALT1LMNAHPGD | |
| SCHEMBL16334972 | 0.75 | MALT1 (0.41) | PKMMALT1LMNAHPGDNFE2L2 | |
| SCHEMBL15075056 | 0.73 | TRPV1 (0.37) | PKMPKLRMALT1LMNAHPGD | |
| SCHEMBL30888679 | 0.73 | AKT1 (0.32) | PKMPKLRMALT1NFE2L2AKT1 | |
| SCHEMBL9333780 | 0.70 | HPGD (0.40) | PKMMALT1LMNAHPGDNFE2L2 | |
| SCHEMBL2860257 | 0.70 | IDO1 (0.36) | PKMMALT1LMNAHPGDNFE2L2 | |
| SCHEMBL25166194 | 0.69 | PARP1 (0.37) | — | |
| SCHEMBL23423365 | 0.69 | AKT1 (0.41) | PKMPKLRMALT1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510497-A | DGK zeta inhibitors | 山东轩竹医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |