Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.74 |
| ▸ | BCR | P11274 | 1/20 | 0.71 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722106 | 1.00 | ABL1 (0.75) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15388503 | 0.89 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL19904364 | 0.89 | ABL1 (0.78) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15388504 | 0.89 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL29421227 | 0.89 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15388565 | 0.89 | ABL1 (0.74) | ABL1KCNH2BCRCRBN | |
| SCHEMBL20419106 | 0.88 | ABL1 (0.70) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15391895 | 0.87 | ABL1 (0.80) | ABL1KCNH2BCRCRBN | |
| SCHEMBL15391894 | 0.87 | ABL1 (0.80) | ABL1KCNH2BCRCRBN | |
| SCHEMBL28717834 | 0.86 | ABL1 (0.70) | ABL1KCNH2BCRCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149409-B | (hetero) aryl amide compound with protein kinase inhibition activity | 中国药科大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-115109048-B | (hetero) aryl amide compound | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-115109048-A | (hetero) aryl amide compound | 中国药科大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-114149409-A | (hetero) aryl amide compound with protein kinase inhibitory activity | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |