Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | EDNRB | P24530 | 3/20 | 0.48 |
| ▸ | EDNRA | P25101 | 3/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29652584 | 0.91 | KMT2A (0.62) | KMT2AKAT6ABRD4EPHX2EDNRB | |
| SCHEMBL21609232 | 0.91 | KMT2A (0.62) | KMT2AKAT6ABRD4EPHX2EDNRB | |
| SCHEMBL21609230 | 0.87 | KMT2A (0.61) | KMT2AKAT6ABRD4EPHX2EDNRB | |
| SCHEMBL29652523 | 0.87 | KMT2A (0.61) | KMT2AKAT6ABRD4EPHX2EDNRB | |
| SCHEMBL21641915 | 0.84 | KMT2A (0.61) | KMT2AKAT6ACCNT1CDK9SMN1; SMN2 | |
| SCHEMBL29652512 | 0.83 | KMT2A (0.66) | KMT2AKAT6AEPHX2SMN1; SMN2LMNA | |
| SCHEMBL21641925 | 0.83 | KMT2A (0.66) | KMT2AKAT6AEPHX2SMN1; SMN2LMNA | |
| SCHEMBL21641931 | 0.82 | KMT2A (0.65) | KMT2AKAT6AEDNRBEDNRACCNT1 | |
| SCHEMBL29652492 | 0.82 | KMT2A (0.65) | KMT2AKAT6AEDNRBEDNRACCNT1 | |
| SCHEMBL21641913 | 0.81 | KMT2A (0.61) | KMT2AKAT6ABRD4EPHX2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364672-A | Benzisoxazole sulfonamide derivatives | 辉瑞大药厂 | 2022-04-15 | — | — | CN | disclosed |