Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.60 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29077485 | 0.90 | CRBN (0.57) | DDB1CRBNIKZF3 | |
| SCHEMBL21997901 | 0.88 | CRBN (0.57) | DDB1CRBNIKZF3 | |
| SCHEMBL23945945 | 0.87 | DDB1 (0.56) | DDB1CRBNIKZF3 | |
| Hydrochloric Acid SCHEMBL31134510 | 0.87 | CRBN (0.56) | DDB1CRBNIKZF3 | |
| SCHEMBL21998308 | 0.87 | DDB1 (0.56) | DDB1CRBNIKZF3 | |
| SCHEMBL23807731 | 0.87 | DDB1 (0.56) | DDB1CRBNIKZF3 | |
| SCHEMBL30692353 | 0.87 | DDB1 (0.56) | DDB1CRBNIKZF3 | |
| SCHEMBL21759957 | 0.87 | DDB1 (0.67) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL22790728 | 0.87 | DDB1 (0.67) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL22525688 | 0.87 | DDB1 (0.67) | DDB1CRBNIKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437035-A | Compound for inhibiting and degrading IRAK4, pharmaceutical composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-05-06 | — | — | CN | disclosed |