Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.42 |
| ▸ | IGF1R | P08069 | 8/20 | 0.41 |
| ▸ | INSR | P06213 | 7/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153747 | 0.84 | ALK (0.51) | ALKIGF1RINSRULK1EGFR | |
| SCHEMBL26087117 | 0.79 | EGFR (0.41) | ALKEGFRPTK2 | |
| SCHEMBL28736076 | 0.79 | ALK (0.46) | ALKIGF1RINSREGFR | |
| SCHEMBL28736084 | 0.78 | ALK (0.42) | ALKIGF1RINSREGFR | |
| SCHEMBL28736081 | 0.78 | ALK (0.41) | ALKIGF1RINSRULK1EGFR | |
| SCHEMBL23153788 | 0.76 | ALK (0.52) | ALKIGF1RINSRULK1EGFR | |
| SCHEMBL28736069 | 0.76 | ALK (0.40) | ALKIGF1RINSREGFR | |
| SCHEMBL28736062 | 0.76 | ALK (0.40) | ALKIGF1RINSREGFR | |
| SCHEMBL23153805 | 0.75 | ALK (0.53) | ALKIGF1RINSREGFR | |
| SCHEMBL23153846 | 0.74 | EGFR (0.57) | ALKIGF1RINSREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502564-A | EGFR inhibitor, composition and preparation method thereof | 贝达药业股份有限公司 | 2022-05-13 | — | — | CN | disclosed |