Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27858396 | 0.92 | CA1 (0.61) | CA1LMNAALDH1A1CA4TP53 | |
| Acetic Acid SCHEMBL11845232 | 0.92 | — | — | |
| Acetic Acid SCHEMBL27840865 | 0.92 | CA1 (0.61) | CA1LMNAALDH1A1CA4TP53 | |
| Acetic Acid SCHEMBL29903085 | 0.92 | — | — | |
| Acetic Acid SCHEMBL29160386 | 0.92 | CA1 (0.61) | CA1LMNAALDH1A1CA4TP53 | |
| Acetic Acid SCHEMBL1695944 | 0.92 | — | — | |
| Acetic Acid SCHEMBL3048949 | 0.89 | CA1 (0.64) | CA1LMNAALDH1A1CA4TP53 | |
| Acetic Acid SCHEMBL11574110 | 0.88 | — | — | |
| L-Lactic Acid SCHEMBL1741442 | 0.86 | CA1 (0.53) | CA1CA4TP53CA2TSHR | |
| Acetic Acid SCHEMBL27873810 | 0.86 | CA1 (0.60) | CA1LMNAALDH1A1CA4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114351125-A | Zirconium oxide-based corrosion-resistant and wear-resistant coating on surface of magnesium alloy and preparation method thereof | 太原科技大学 | 2022-04-15 | — | — | CN | disclosed |