Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CPS1 | P31327 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28915964 | 1.00 | TSHR (0.39) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL28915023 | 1.00 | TSHR (0.39) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL20279557 | 0.88 | TSHR (0.41) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL21354258 | 0.86 | TSHR (0.41) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL17061936 | 0.86 | TSHR (0.41) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL17061934 | 0.86 | TSHR (0.41) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL16009932 | 0.85 | TSHR (0.39) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL28572878 | 0.85 | TSHR (0.39) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL16010481 | 0.85 | TSHR (0.39) | TSHRLMNAALOX15HSD17B10L3MBTL1 | |
| SCHEMBL7995036 | 0.84 | TSHR (0.41) | TSHRLMNAALOX15HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322158-A | As KRAS G12C Substituted quinazoline compounds of protein inhibitor | 江南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-1277824-C | Piperazine derivatives | HOFFMANN LA ROCHE (CH) | 2006-10-04 | — | — | CN | disclosed |
| CN-1533382-A | Piperazine derivatives | - | 2004-09-29 | — | — | CN | disclosed |