SCHEMBL28746586

SCHEMBL28746586

O=C(CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O)NCCc1cncn1C(=O)O

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.84
F2 P00734 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1651827 0.91 F10 (1.00) F10
SCHEMBL1652617 0.91 F10 (0.81) F10F2
SCHEMBL1651557 0.85 F10 (1.00) F10F2
SCHEMBL1652352 0.84 F10 (1.00) F10F2
SCHEMBL1654679 0.84 F10 (1.00) F10F2
SCHEMBL1654406 0.83 F10 (0.81) F10
SCHEMBL1653567 0.81 F10 (1.00) F10
SCHEMBL1653332 0.81 F10 (0.74) F10F2
SCHEMBL1652491 0.81 F10 (1.00) F10
SCHEMBL1654571 0.81 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1291892-A Substituted oxoazaheterocyclyl factor Xa inhibitors AWENTIS PHARMACEUTICAL INC (US) 2001-04-18 CN disclosed