Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | THPO | P40225 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | CETP | P11597 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | UBE2N | P61088 | 1/20 | 0.66 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27591440 | 1.00 | CYP2D6 (0.66) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL10954492 | 1.00 | CYP2D6 (0.66) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL5274787 | 0.96 | CYP2D6 (0.66) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL10408562 | 0.96 | CYP2D6 (0.66) | CYP2D6SPHK1GMNNLMNAPOLB | |
| Hydrochloric Acid SCHEMBL5274824 | 0.94 | CYP2D6 (0.63) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL16859678 | 0.92 | CYP2D6 (0.76) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL16859677 | 0.92 | CYP2D6 (0.76) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL16104483 | 0.92 | CYP2D6 (0.76) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL6118653 | 0.92 | CYP2D6 (0.76) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL6118549 | 0.92 | CYP2D6 (0.76) | CYP2D6SPHK1GMNNLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1433478-A | Colloidal synthetic vector for gene therapy | NOVARTIS AG (CH) | 2003-07-30 | — | — | CN | disclosed |