Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | APOB | P04114 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867756 | 0.90 | NPSR1 (0.48) | SMYD3APOBKMT2AMEN1POLB | |
| SCHEMBL866767 | 0.87 | FYN (0.67) | FYNHDAC1APOBMTTPGRIN2B | |
| SCHEMBL5439855 | 0.73 | NPC1 (0.56) | SMYD3KMT2AMEN1MAPT | |
| SCHEMBL3834622 | 0.70 | GRIN2B (0.77) | FYNHDAC1GRIN2BKMT2AMEN1 | |
| SCHEMBL26537824 | 0.70 | GRM5 (0.66) | SSTR3 | |
| Hydrochloric Acid SCHEMBL10446804 | 0.69 | GRIN2B (0.74) | FYNGRIN2BKMT2AMEN1 | |
| SCHEMBL865974 | 0.68 | FYN (0.69) | FYNHDAC1GRIN2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10447028 | 0.68 | FYN (0.63) | FYNGRIN2BKMT2AMEN1POLB | |
| SCHEMBL6359692 | 0.68 | CA1 (0.58) | KMT2AMEN1MAPT | |
| SCHEMBL28198558 | 0.67 | MEN1 (0.56) | HSD17B10HDAC1SMYD3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353692-A | Betz 2-adrenoceptor agonists | NOVARTIS AG (CH) | 2002-06-12 | — | — | CN | disclosed |