Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29731444 | 0.93 | ACACB (0.48) | ACACBEPHX2MEN1KMT2ATP53 | |
| SCHEMBL23163989 | 0.93 | ACACB (0.48) | ACACBEPHX2MEN1KMT2ATP53 | |
| SCHEMBL27078186 | 0.91 | ACACB (0.47) | ACACBEPHX2MEN1KMT2ATP53 | |
| SCHEMBL23163675 | 0.91 | ACACB (0.47) | ACACBEPHX2MEN1KMT2ATP53 | |
| SCHEMBL27077961 | 0.90 | ACACB (0.46) | ACACBEPHX2MEN1KMT2ATP53 | |
| SCHEMBL29705567 | 0.90 | ACACB (0.47) | ACACBEPHX2MEN1KMT2ATP53 | |
| SCHEMBL27077963 | 0.90 | ACACB (0.47) | ACACBEPHX2MEN1KMT2ATP53 | |
| SCHEMBL23163713 | 0.89 | ACACB (0.47) | ACACBEPHX2ABHD6MGLLPDE9A | |
| SCHEMBL29703881 | 0.89 | TP53 (0.44) | ACACBEPHX2MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL29705662 | 0.88 | TP53 (0.43) | ACACBEPHX2MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |