Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 14/20 | 0.57 |
| ▸ | CDK2 | P24941 | 14/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 14/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.57 |
| ▸ | CCND1 | P24385 | 1/20 | 0.57 |
| ▸ | CDK7 | P50613 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | CCNH | P51946 | 1/20 | 0.57 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.57 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570477 | 0.92 | CCNE1 (0.66) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL28747888 | 0.91 | CDK2 (0.57) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27586861 | 0.91 | CCNE1 (0.51) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27570480 | 0.89 | CCNE1 (0.55) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27567511 | 0.88 | CDK2 (0.53) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27586858 | 0.86 | CCNE1 (0.55) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27577760 | 0.86 | CCNE1 (0.48) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27586859 | 0.85 | CDK2 (0.51) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27586856 | 0.85 | CCNE1 (0.51) | CCNE1CDK2CDK5ALDH1A1CCNT1 | |
| SCHEMBL27567526 | 0.85 | CCNE1 (0.51) | CCNE1CDK2CDK5ALDH1A1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1425009-A | Arylmethyl-carbonylamino-thiazole derivatives and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2003-06-18 | — | — | CN | claimed |
| CN-1425009-A | Arylmethyl-carbonylamino-thiazole derivatives and their use as antitumor agents | PHARMACIA & UPJOHN SPA (IT) | 2003-06-18 | — | — | CN | disclosed |