Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 15/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170154 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074395 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074399 | 1.00 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074148 | 0.92 | ADRB3 (0.85) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074142 | 0.92 | ADRB3 (0.85) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074276 | 0.91 | ADRB3 (0.83) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074267 | 0.91 | ADRB3 (0.83) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7167677 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL28751611 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074181 | 0.89 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1455771-A | Cyclic amine phenyl Beta-3 adrenergic receptor agonists | WYETH LTD (US) | 2003-11-12 | — | — | CN | claimed |
| CN-1455771-A | Cyclic amine phenyl Beta-3 adrenergic receptor agonists | WYETH LTD (US) | 2003-11-12 | — | — | CN | disclosed |