Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.60 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | MC4R | P32245 | 1/20 | 0.60 |
| ▸ | FAP | Q12884 | 1/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.60 |
| ▸ | GHSR | Q92847 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL556428 | 0.96 | DPP4 (0.82) | DPP4CHRM1CHRM3CHRM2KCNH2 | |
| SCHEMBL555521 | 0.94 | DPP4 (0.85) | DPP4CHRM1CHRM3CHRM2KCNH2 | |
| SCHEMBL555576 | 0.94 | DPP4 (0.76) | DPP4CHRM1CHRM3CHRM2KCNH2 | |
| SCHEMBL27583065 | 0.92 | DPP4 (0.75) | DPP4CHRM1CHRM3CHRM2KCNH2 | |
| SCHEMBL556151 | 0.92 | DPP4 (0.77) | DPP4CHRM1CHRM3POU2F2ADORA3 | |
| SCHEMBL28346678 | 0.92 | DPP4 (0.77) | DPP4CHRM1CHRM3POU2F2ADORA3 | |
| SCHEMBL555833 | 0.90 | DPP4 (1.00) | DPP4CHRM1CHRM3CHRM2KCNH2 | |
| SCHEMBL4668687 | 0.90 | DPP4 (0.71) | DPP4 | |
| SCHEMBL555375 | 0.90 | DPP4 (1.00) | DPP4CHRM1CHRM3CHRM2KCNH2 | |
| SCHEMBL554218 | 0.90 | DPP4 (1.00) | DPP4CHRM1CHRM3CHRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101293888-B | Xanthine derivative, production and use thereof as a medicament | BOEHRINGER INGELHEIM PHARMA | 2013-09-25 | — | — | CN | disclosed |
| CN-101293888-A | Xanthine derivative, production and use thereof as a medicament | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-10-29 | — | — | CN | disclosed |
| CN-100408579-C | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-08-06 | — | — | CN | disclosed |
| CN-1492870-A | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-04-28 | — | — | CN | disclosed |