Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | OTC | P00480 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 7/20 | 0.49 |
| ▸ | NOS1 | P29475 | 5/20 | 0.49 |
| ▸ | NOS3 | P29474 | 4/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.47 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880728 | 1.00 | GSR (0.52) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL43287 | 1.00 | GSR (0.52) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL10071054 | 1.00 | GSR (0.52) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL27615800 | 1.00 | GSR (0.52) | GSROTCNOS2NOS1NOS3 | |
| Arginine SCHEMBL5152371 | 0.98 | OTC (0.53) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL4221548 | 0.98 | GSR (0.50) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL4225929 | 0.98 | GSR (0.50) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL4225043 | 0.98 | GSR (0.50) | GSROTCNOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL21045047 | 0.98 | GSR (0.50) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL4405593 | 0.98 | GSR (0.50) | GSROTCNOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100365014-C | Tumor targeting agents and uses thereof | KARYON OY (FI) | 2008-01-30 | — | — | CN | disclosed |
| CN-101027316-A | Tumor targeting agent and application thereof | KARYON OY (FI) | 2007-08-29 | — | — | CN | disclosed |
| CN-1720259-A | Tumor targeting agents and uses thereof | KARYON OY (FI) | 2006-01-11 | — | — | CN | disclosed |