Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690781 | 0.88 | MAPK14 (0.38) | MAPK14SRCSYKPKMMAPT | |
| SCHEMBL14612535 | 0.81 | POLB (0.35) | PKMMAPTMEN1ALDH1A1GAA | |
| SCHEMBL689446 | 0.80 | MAPT (0.41) | MAPK14PKMMAPTMEN1ALDH1A1 | |
| SCHEMBL16829546 | 0.78 | GSK3A (0.40) | MAPK14SRCSYKGSK3A | |
| SCHEMBL690103 | 0.75 | POLB (0.44) | PKMMAPTMEN1ALDH1A1GAA | |
| SCHEMBL16829293 | 0.75 | SRC (0.38) | MAPK14SRCSYKPKMMAPT | |
| SCHEMBL16829559 | 0.74 | SRC (0.42) | MAPK14SRCSYKGSK3A | |
| SCHEMBL1935976 | 0.74 | CYP2C19 (0.53) | PKMMAPTMEN1ALDH1A1GAA | |
| SCHEMBL1934356 | 0.74 | MEN1 (0.36) | PKMMAPTMEN1ALDH1A1GAA | |
| SCHEMBL15743701 | 0.74 | MAPK14 (0.37) | MAPK14SRCSYKALDH1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717162-A | Urea derivatives as kinase inhibitors | 奥苏拉收购有限公司 | 2021-11-30 | — | — | CN | disclosed |