Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635860 | 0.70 | KMT2A (0.33) | — | |
| SCHEMBL3576164 | 0.70 | MAP2K1 (0.46) | MAP2K1 | |
| SCHEMBL16828396 | 0.68 | PARP1 (0.36) | MAP2K1 | |
| SCHEMBL28525247 | 0.66 | CYP2D6 (0.34) | — | |
| SCHEMBL27631378 | 0.66 | PARP10 (0.55) | — | |
| SCHEMBL28317948 | 0.64 | HCAR2 (0.38) | — | |
| SCHEMBL27361577 | 0.63 | CTNNB1 (0.51) | — | |
| SCHEMBL3641757 | 0.62 | KMT2A (0.34) | — | |
| SCHEMBL27499828 | 0.62 | — | — | |
| SCHEMBL5473633 | 0.61 | HAO1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585609-A | 2H-indazole derivatives and their use in the treatment of diseases | 比奥根MA公司 | 2022-06-03 | — | — | CN | disclosed |