Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 18/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 18/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 18/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 18/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 18/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 18/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 18/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 18/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 18/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994769 | 0.90 | HDAC1 (0.51) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5994755 | 0.90 | HDAC1 (0.51) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5991350 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5992922 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5992932 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5992279 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5992286 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5992420 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5991345 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5992429 | 0.89 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1805930-A | Hydroxamic acids useful in the treatment of hyper-proliferative disorders | BAYER PHARMACEUTICALS CORP (US) | 2006-07-19 | — | — | CN | disclosed |