Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.52 |
| ▸ | SYK | P43405 | 12/20 | 0.49 |
| ▸ | ITK | Q08881 | 3/20 | 0.45 |
| ▸ | BTK | Q06187 | 3/20 | 0.43 |
| ▸ | BMX | P51813 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655719 | 0.80 | EGFR (0.68) | EGFRSYKITKBTK | |
| SCHEMBL655718 | 0.80 | EGFR (0.68) | EGFRSYKITKBTK | |
| SCHEMBL655883 | 0.80 | EGFR (0.67) | EGFRSYKITKBTK | |
| SCHEMBL660419 | 0.79 | EGFR (0.60) | EGFRSYKITKBTKBMX | |
| SCHEMBL660418 | 0.79 | EGFR (0.60) | EGFRSYKITKBTKBMX | |
| SCHEMBL658785 | 0.78 | EGFR (0.67) | EGFRSYKITKBTK | |
| SCHEMBL654535 | 0.77 | SYK (0.61) | EGFRSYKITKBTK | |
| SCHEMBL654536 | 0.77 | SYK (0.61) | EGFRSYKITKBTK | |
| SCHEMBL28757175 | 0.77 | SYK (0.48) | EGFRSYKITKBTK | |
| SCHEMBL655867 | 0.76 | EGFR (0.64) | EGFRSYKITKBTKBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |