Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 8/20 | 0.53 |
| ▸ | SYK | P43405 | 7/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | STK17B | O94768 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2100711 | 0.92 | BCL6 (0.62) | BCL6SYKNCOR2AURKAEGFR | |
| SCHEMBL2104497 | 0.81 | SYK (0.59) | BCL6SYKNCOR2EGFRSTK17B | |
| SCHEMBL2100597 | 0.79 | SYK (0.64) | SYKAURKA | |
| SCHEMBL655635 | 0.78 | BCL6 (0.80) | BCL6SYKNCOR2AURKAEGFR | |
| SCHEMBL28757204 | 0.77 | AURKA (0.42) | BCL6SYKNCOR2AURKAEGFR | |
| SCHEMBL28753659 | 0.76 | SYK (0.52) | SYKAURKA | |
| SCHEMBL657386 | 0.75 | SYK (0.71) | BCL6SYKNCOR2AURKAEGFR | |
| SCHEMBL2102179 | 0.74 | BCL6 (0.72) | BCL6SYKNCOR2AURKAEGFR | |
| SCHEMBL2101082 | 0.74 | BCL6 (0.72) | BCL6SYKNCOR2AURKAEGFR | |
| SCHEMBL2100643 | 0.74 | BCL6 (0.72) | BCL6SYKNCOR2AURKASTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |