⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15950308 | 0.88 | — | — | |
| SCHEMBL94079 | 0.83 | — | — | |
| SCHEMBL15950033 | 0.80 | — | — | |
| SCHEMBL15400691 | 0.79 | — | — | |
| SCHEMBL9807793 | 0.79 | — | — | |
| SCHEMBL15400603 | 0.79 | — | — | |
| SCHEMBL15949990 | 0.77 | — | — | |
| SCHEMBL15950089 | 0.77 | — | — | |
| SCHEMBL2675596 | 0.75 | — | — | |
| SCHEMBL4289784 | 0.74 | ESR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1579845-B1 | Cosmetic composition comprising a polyglycerolated silicone elastomer | L'ORÉAL (FR) | 2017-04-19 | — | — | EP | disclosed |
| CN-1781476-B | Cosmetic composition containing silicone elastomer bound to polyglycerol | OREAL | 2013-10-16 | — | — | CN | disclosed |
| US-7842285-B2 | cosmetic formulation containing a phenyl substituted organosiloxane and sucrose acetate isobutyrate to provide shine and/or gloss when applied to a keratinous material, such as skin | L'OREAL (FR) | 2010-11-30 | — | — | US | disclosed |
| CN-100415204-C | Cosmetic compositions and methods of use | OREAL (FR) | 2008-09-03 | — | — | CN | disclosed |
| US-7378103-B2 | Cosmetic composition comprising a polyglycerolated silicone elastomer | L'OREAL (FR) | 2008-05-27 | — | — | US | disclosed |
| US-20060228314-A1 | Cosmetic compositions containing phenyl silicones | REVLON CONSUMER PRODUCTS CORPORATION | 2006-10-12 | — | — | US | disclosed |
| CN-1823711-A | Cosmetic compositions and methods of use | OREAL (FR) | 2006-08-30 | — | — | CN | disclosed |
| CN-1781476-A | Cosmetic composition containing silicone elastomer bound to polyglycerol | OREAL (FR) | 2006-06-07 | — | — | CN | disclosed |
| EP-1661549-A1 | Cosmetic compositions and methods of use | L'OREAL (FR) | 2006-05-31 | — | — | EP | disclosed |
| US-20060110347-A1 | Cosmetic compositions and methods of use | L'OREAL (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20050220728-A1 | Cosmetic composition comprising a polyglycerolated silicone elastomer | KANJI MOHAMED | 2005-10-06 | — | — | US | disclosed |
| EP-1579845-A2 | Cosmetic composition comprising a polyglycerolated silicone elastomer | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004071438-A2 | COSMETIC COMPOSITIONS CONTAINING PHENYL SILICONES | REVLON CONSUMER PRODUCTS CORPORATION (US) | 2004-08-26 | — | — | WO | disclosed |
| US-20040151680-A1 | Cosmetic compositions containing phenyl silicones | REVLON CONSUMER PRODUCTS CORPORATION | 2004-08-05 | — | — | US | disclosed |