Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617934 | 0.89 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11GFER | |
| SCHEMBL27617939 | 0.89 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11GFER | |
| SCHEMBL5008768 | 0.86 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11GFER | |
| SCHEMBL27654182 | 0.86 | DHODH (0.44) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL27637093 | 0.85 | MAPT (0.43) | GFERMAPTJAK2 | |
| SCHEMBL5007743 | 0.83 | CLCN2 (0.51) | MAPK14MAPK13MAPK12MAPK11GFER | |
| SCHEMBL27637099 | 0.81 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11JAK2 | |
| SCHEMBL5010659 | 0.79 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11GFER | |
| SCHEMBL5010753 | 0.79 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11CLCN2 | |
| SCHEMBL5008506 | 0.79 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100448869-C | Anilinopyrazole derivatives for the treatment of diabetes | BAYER PHARMACEUTICALS CORP (US) | 2009-01-07 | — | — | CN | claimed |
| CN-1717401-A | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORP (US) | 2006-01-04 | — | — | CN | claimed |
| CN-100448869-C | Anilinopyrazole derivatives for the treatment of diabetes | BAYER PHARMACEUTICALS CORP (US) | 2009-01-07 | — | — | CN | disclosed |
| CN-1717401-A | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORP (US) | 2006-01-04 | — | — | CN | disclosed |