Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666988 | 0.83 | TRPV1 (0.54) | TRPV1GAA | |
| SCHEMBL2723776 | 0.82 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL10308206 | 0.81 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL10307966 | 0.81 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL14020902 | 0.81 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL20411718 | 0.81 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL10307946 | 0.80 | TRPV1 (0.77) | TRPV1 | |
| SCHEMBL19055806 | 0.79 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL14406332 | 0.79 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL27666948 | 0.79 | TRPV1 (0.45) | TRPV1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1874775-A | 4-fluoro-4-(pyridin-2-yl)-piperidine-1-carboxamide derivatives and related compounds which modulate the function of the vanilloid-1 receptor (VR1) for the treatment of pain | MERCK SHARP & DOHME (GB) | 2006-12-06 | — | — | CN | claimed |
| CN-1874775-A | 4-fluoro-4-(pyridin-2-yl)-piperidine-1-carboxamide derivatives and related compounds which modulate the function of the vanilloid-1 receptor (VR1) for the treatment of pain | MERCK SHARP & DOHME (GB) | 2006-12-06 | — | — | CN | disclosed |