Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585113 | 0.89 | ADORA2A (0.49) | ADORA2AADORA1ADORA2B | |
| SCHEMBL4584106 | 0.87 | ADORA2A (0.47) | ADORA2AADORA1ADORA2B | |
| SCHEMBL4584042 | 0.85 | ADORA2A (0.49) | ADORA2AADORA1ADORA2B | |
| SCHEMBL4584769 | 0.84 | ADORA2A (0.47) | ADORA2AADORA1ADORA2B | |
| SCHEMBL4583361 | 0.83 | ADORA2A (0.46) | ADORA2AADORA1 | |
| SCHEMBL4584817 | 0.81 | ADORA2A (0.51) | ADORA2AADORA1 | |
| SCHEMBL4585347 | 0.81 | ADORA2A (0.53) | ADORA2AADORA1ADORA2B | |
| SCHEMBL4585332 | 0.81 | ADORA2A (0.48) | ADORA2AADORA1 | |
| SCHEMBL4584074 | 0.81 | ADORA2A (0.50) | ADORA2AADORA1 | |
| SCHEMBL4584514 | 0.81 | ADORA2A (0.50) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1871231-A | Pyrazine derivatives and pharmaceutical use thereof | ASTELLAS PHARMA INC (JP) | 2006-11-29 | — | — | CN | disclosed |