Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28759336 | 1.00 | MCHR1 (0.42) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6879692 | 0.93 | MCHR1 (0.43) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6879698 | 0.93 | MCHR1 (0.43) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27632408 | 0.90 | MCHR1 (0.43) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27632405 | 0.90 | MCHR1 (0.43) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27632493 | 0.90 | MCHR1 (0.42) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27632492 | 0.90 | MCHR1 (0.42) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27652704 | 0.84 | MCHR1 (0.44) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27652702 | 0.84 | MCHR1 (0.44) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27652790 | 0.84 | MCHR1 (0.44) | MCHR1ADRA2AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1798736-A | Novel quinoline, tetrahydroquinazoline and pyrimidine derivatives and methods of treatment related to their use | ARENA PHARM INC (JP) | 2006-07-05 | — | — | CN | disclosed |