Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29783553 | 1.00 | PRCP (0.72) | PRCPHDAC1HDAC8DRD1KDM4E | |
| SCHEMBL13928812 | 0.84 | PRCP (1.00) | PRCPHDAC1HDAC8DRD1HDAC2 | |
| SCHEMBL8415128 | 0.84 | PRCP (1.00) | PRCPHDAC1HDAC8DRD1HDAC2 | |
| SCHEMBL28942533 | 0.83 | PRCP (0.64) | PRCPDRD1CA1CA2CA9 | |
| SCHEMBL29783557 | 0.83 | PRCP (0.64) | PRCPDRD1CA1CA2CA9 | |
| SCHEMBL4455643 | 0.82 | PRCP (0.77) | PRCPDRD1DRD2 | |
| SCHEMBL30965968 | 0.82 | PRCP (0.77) | PRCPDRD1KDM4EDRD2 | |
| SCHEMBL22784853 | 0.82 | PRCP (0.77) | PRCPDRD1KDM4EDRD2 | |
| SCHEMBL29783569 | 0.82 | PRCP (0.77) | PRCPDRD1KDM4EDRD2 | |
| SCHEMBL5245455 | 0.82 | PRCP (0.77) | PRCPDRD1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516835-A | Synthetic method of alpha, alpha-disubstituted tetrahydroisoquinoline compounds | 西安石油大学 | 2022-05-20 | — | — | CN | disclosed |