SCHEMBL28759609

SCHEMBL28759609

OB(O)c1cc2ccccc2c2c1ccc1ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.47
HPGD P15428 3/20 0.47
HIF1A Q16665 2/20 0.47
TSHR P16473 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP1 P29466 1/20 0.47
RAB9A P51151 1/20 0.47
CASP7 P55210 1/20 0.47
ATM Q13315 1/20 0.47
ALDH1A1 P00352 5/20 0.46
CYP1B1 Q16678 2/20 0.46
MAPT P10636 2/20 0.46
HPRT1 P00492 1/20 0.44
CYP1A2 P05177 4/20 0.42
FYN P06241 2/20 0.42
ACHE P22303 2/20 0.42
AHR P35869 2/20 0.42
ERBB2 P04626 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29628999 1.00 HSD17B10 (0.47) HSD17B10HPGDHIF1ATSHRL3MBTL1
SCHEMBL22155490 0.89 CYP1A2 (0.48) HSD17B10HPGDHIF1ATSHRL3MBTL1
SCHEMBL31286359 0.89 CYP1A2 (0.48) HSD17B10HPGDHIF1ATSHRL3MBTL1
SCHEMBL29629019 0.84 HSD17B10 (0.42) HSD17B10HPGDHIF1ATSHRL3MBTL1
SCHEMBL1375269 0.84 HSD17B10 (0.42) HSD17B10HPGDHIF1ATSHRL3MBTL1
SCHEMBL18201405 0.81 CYP1B1 (0.40) HSD17B10HPGDHIF1ATSHRL3MBTL1
SCHEMBL16211089 0.80 MAPT (0.44) HPGDALDH1A1MAPT
SCHEMBL368234 0.79 TRPM4 (0.54) HSD17B10HPGDHIF1ATSHRCYP3A4
SCHEMBL1816278 0.78 CYP1A2 (0.65) HSD17B10HPGDHIF1ATSHRL3MBTL1
SCHEMBL19583437 0.78 NPC1 (0.40) HSD17B10HPGDTSHRL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114656481-A Organic material and application thereof 北京燕化集联光电技术有限公司 2022-06-24 CN disclosed