Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914982 | 0.89 | GUCY1B2 (0.58) | GSK3BPIN1MAPK1ALDH1A1TDP1 | |
| SCHEMBL2248943 | 0.89 | ABCG2 (0.53) | GSK3BPIN1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11834671 | 0.85 | GSK3B (0.65) | GSK3BPIN1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL9383640 | 0.81 | GALR2 (0.60) | SMN1; SMN2MAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL11837349 | 0.79 | GSK3B (0.57) | GSK3BPIN1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL10814332 | 0.78 | GSK3B (0.56) | GSK3BPIN1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL29695661 | 0.76 | GSK3B (0.61) | GSK3BPIN1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL11838370 | 0.75 | GSK3B (0.53) | GSK3BPIN1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL2572184 | 0.74 | GSK3B (0.58) | GSK3BPIN1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL10810171 | 0.74 | GSK3B (0.58) | GSK3BPIN1SMN1; SMN2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1830964-B | 4-Substituting anilino-3-nitroquinoline compounds, prepn. method and use thereof | SHANGHAI INST OF MEDICINES CHINESE ACADEMY OF SCIENCES | 2011-06-15 | — | — | CN | disclosed |
| CN-1830964-A | 4-Substituting anilino-3-nitroquinoline compounds, prepn. method and use thereof | SHANGHAI INST OF MEDICINES CHI (CN) | 2006-09-13 | — | — | CN | disclosed |