SCHEMBL28760187

SCHEMBL28760187

Fc1ccc([SnH])cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27730518 0.78
2,4-Dichlorofluorobenzene SCHEMBL29481133 0.77
SCHEMBL27881232 0.77
2,4-Dichlorofluorobenzene SCHEMBL530773 0.77
SCHEMBL17552697 0.76
SCHEMBL6206442 0.74
SCHEMBL167260 0.74
SCHEMBL29415159 0.74
2,4-Dichlorofluorobenzene SCHEMBL28533905 0.74 TP53 (0.55)
SCHEMBL14128374 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1964975-B Hiv integrase inhibitors MERCK SHARP & DOHME CORP. (US) 2011-11-30 CN disclosed
CN-101796027-A N-piperidin-4-ylmethyl-amide derivatives and their use as monoamine neurotransmitter re-uptake inhibitors NEUROSEARCH AS 2010-08-04 CN disclosed
CN-100368409-C 8-azabicyclo [3.2.1] octane derivatives and their use for the preparation of monoamine neurotransmitter re-uptake inhibitors NEUROSEARCH AS (DK) 2008-02-13 CN disclosed
CN-1964975-A HIV integrase inhibitors MERCK & CO INC (US) 2007-05-16 CN disclosed
CN-1798745-A Novel 8-aza-bicyclo not 3.2.1|octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors NEUROSEARCH AS (DK) 2006-07-05 CN disclosed