Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 14/20 | 0.69 |
| ▸ | ESR1 | P03372 | 13/20 | 0.69 |
| ▸ | ESRRB | O95718 | 6/20 | 0.69 |
| ▸ | ESRRA | P11474 | 6/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638498 | 0.85 | ESR2 (0.71) | ESR2ESR1ESRRBESRRAQPCT | |
| SCHEMBL27638529 | 0.84 | ESR2 (0.69) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL3936450 | 0.82 | ESR1 (1.00) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL27638502 | 0.82 | ESR2 (0.71) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL6534483 | 0.81 | ESR1 (0.84) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL27659332 | 0.81 | ESR2 (0.71) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL27659338 | 0.81 | ESR2 (0.71) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL27638489 | 0.80 | ESR2 (0.44) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL27659336 | 0.80 | ESR1 (0.72) | ESR2ESR1ESRRBESRRAPOLB | |
| SCHEMBL27638507 | 0.77 | ESR2 (0.49) | ESR2ESR1ESRRBESRRAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | claimed |
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | disclosed |