SCHEMBL28762008

SCHEMBL28762008

CCCCCCCCC1([Hf](C)C)C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
PKM P14618 1/20 0.34
MMP2 P08253 4/20 0.33
MMP9 P14780 4/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
GAA P10253 2/20 0.31
MEN1 O00255 1/20 0.31
ALOX12 P18054 1/20 0.31
KMT2A Q03164 1/20 0.31
SIGMAR1 Q99720 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SETD7 Q8WTS6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28761952 1.00 KDM4E (0.34) KDM4EPKMMMP2MMP9MMP3
SCHEMBL28761960 1.00 KDM4E (0.34) KDM4EPKMMMP2MMP9MMP3
SCHEMBL28761973 0.98 KDM4E (0.35) KDM4EPKMMMP2MMP9MMP3
SCHEMBL28508421 0.94 KDM4E (0.36) KDM4EPKM
SCHEMBL28497844 0.87 KDM4E (0.34) KDM4EPKM
SCHEMBL28761912 0.81 NPC1 (0.32) KDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL28500286 0.80 KDM4E (0.33) KDM4EPKM
SCHEMBL27948638 0.80 KDM4E (0.35) KDM4EPKM
SCHEMBL6760414 0.78 KDM4E (0.37) KDM4EPKMMMP2MMP9MMP3
SCHEMBL28762028 0.77 GAA (0.32) KDM4EPKMGAAALOX12SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114845980-A Dimer-selective metallocene catalyst, non-aromatic hydrocarbon soluble activator and method for preparing poly alpha-olefin oligomer using the same 埃克森美孚化学专利公司 2022-08-02 CN claimed
CN-114502521-A Process for producing low viscosity polyalphaolefins using non-aromatic hydrocarbon soluble activators 埃克森美孚化学专利公司 2022-05-13 CN claimed
CN-114845980-A Dimer-selective metallocene catalyst, non-aromatic hydrocarbon soluble activator and method for preparing poly alpha-olefin oligomer using the same 埃克森美孚化学专利公司 2022-08-02 CN disclosed
CN-114502521-A Process for producing low viscosity polyalphaolefins using non-aromatic hydrocarbon soluble activators 埃克森美孚化学专利公司 2022-05-13 CN disclosed