Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.88 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.88 |
| ▸ | SRC | P12931 | 5/20 | 0.88 |
| ▸ | FYN | P06241 | 4/20 | 0.88 |
| ▸ | BLK | P51451 | 1/20 | 0.88 |
| ▸ | BMX | P51813 | 1/20 | 0.88 |
| ▸ | JAK3 | P52333 | 1/20 | 0.88 |
| ▸ | BTK | Q06187 | 1/20 | 0.88 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.88 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29717476 | 1.00 | EGFR (0.88) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL2680536 | 0.93 | EGFR (1.00) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL29359583 | 0.93 | EGFR (1.00) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL2996153 | 0.87 | EGFR (1.00) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL28942731 | 0.87 | EGFR (0.88) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL614989 | 0.85 | FYN (1.00) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL31060509 | 0.85 | FYN (1.00) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL3241277 | 0.84 | FYN (0.78) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL7914891 | 0.84 | FYN (0.78) | EGFRERBB2SRCFYNBLK | |
| SCHEMBL2991796 | 0.84 | EGFR (1.00) | EGFRERBB2SRCFYNBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357852-B | Benzopyrimidine compounds, preparation method and application | 中国药科大学 | 2022-06-10 | — | — | CN | disclosed |