Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 18/20 | 0.79 |
| ▸ | CDK4 | P11802 | 18/20 | 0.79 |
| ▸ | CCND1 | P24385 | 18/20 | 0.79 |
| ▸ | CDK2 | P24941 | 17/20 | 0.79 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352584 | 0.88 | CDK1 (1.00) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL27708355 | 0.88 | CDK1 (0.76) | CDK1CDK4CCND1CDK2BTK | |
| SCHEMBL6808274 | 0.87 | CDK1 (0.86) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL4351149 | 0.79 | CDK1 (0.86) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL4348425 | 0.79 | CDK1 (1.00) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL4350490 | 0.79 | CDK1 (1.00) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL4355446 | 0.79 | CDK1 (0.67) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL4352127 | 0.78 | CDK1 (0.78) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL4355780 | 0.78 | CDK1 (1.00) | CDK1CDK4CCND1CDK2 | |
| SCHEMBL4348182 | 0.78 | CDK1 (1.00) | CDK1CDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101044121-A | 4-aminopyrimidine-5-one | HOFFMANN LA ROCHE (CH) | 2007-09-26 | — | — | CN | claimed |
| CN-101044121-A | 4-aminopyrimidine-5-one | HOFFMANN LA ROCHE (CH) | 2007-09-26 | — | — | CN | disclosed |