Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vch-759 Free Acid SCHEMBL5029770 | 1.00 | KDM4E (0.40) | KDM4EHTTATMNR1I2PTPRF | |
| Vch-759 Free Acid SCHEMBL101720 | 1.00 | KDM4E (0.40) | KDM4EHTTATMNR1I2PTPRF | |
| Vch-759 Free Acid SCHEMBL2874237 | 1.00 | KDM4E (0.40) | KDM4EHTTATMNR1I2PTPRF | |
| SCHEMBL2878321 | 0.97 | KDM4E (0.42) | KDM4EHTTATMNR1I2PTPRF | |
| SCHEMBL17635079 | 0.97 | KDM4E (0.42) | KDM4EHTTATMNR1I2PTPRF | |
| SCHEMBL14030913 | 0.95 | NR1I2 (0.39) | KDM4EHTTATMNR1I2PTPRF | |
| SCHEMBL2879448 | 0.95 | NR1I2 (0.39) | KDM4EHTTATMNR1I2PTPRF | |
| SCHEMBL14030938 | 0.94 | KDM4E (0.40) | KDM4EHTTATMNR1I2PTPRF | |
| SCHEMBL2876807 | 0.94 | KDM4E (0.40) | KDM4EHTTATMNR1I2PTPRF | |
| SCHEMBL14030907 | 0.94 | KDM4E (0.40) | KDM4EHTTATMNR1I2PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | disclosed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | disclosed |