Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873337 | 0.93 | PDE5A (0.51) | PDE5AKCNH2 | |
| SCHEMBL2874970 | 0.91 | PDE5A (0.42) | PDE5AKCNH2 | |
| SCHEMBL332006 | 0.90 | PDE5A (0.55) | PDE5AKCNH2 | |
| SCHEMBL330525 | 0.87 | PDE5A (0.55) | PDE5AKCNH2 | |
| SCHEMBL13763168 | 0.87 | PDE5A (0.47) | PDE5AKCNH2 | |
| SCHEMBL331424 | 0.82 | PDE5A (0.57) | PDE5AKCNH2 | |
| SCHEMBL332705 | 0.80 | PDE5A (0.47) | PDE5AKCNH2 | |
| SCHEMBL332816 | 0.80 | PDE5A (0.47) | PDE5AKCNH2 | |
| SCHEMBL10287279 | 0.79 | PDE5A (0.40) | PDE5A | |
| SCHEMBL2873338 | 0.78 | PDE5A (0.55) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689751-B1 | 5,7-DIAMINOPYRAZOLO[4,3-D]PYRIMIDINES WITH PDE-5 INHIBITING ACTIVITY | PFIZER LTD (GB) | 2010-10-20 | — | — | EP | claimed |