Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.64 |
| ▸ | PPARD | Q03181 | 14/20 | 0.64 |
| ▸ | PPARA | Q07869 | 13/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775097 | 0.95 | PPARG (0.57) | PPARGPPARDPPARAMEN1NPC1 | |
| SCHEMBL27733701 | 0.88 | PPARG (0.70) | PPARGPPARDPPARA | |
| SCHEMBL27713458 | 0.87 | PPARG (0.54) | PPARGPPARDPPARA | |
| SCHEMBL27713508 | 0.84 | PPARG (0.54) | PPARGPPARDPPARA | |
| SCHEMBL27733808 | 0.84 | DYRK1A (0.49) | PPARGPPARDPPARANPC1POLB | |
| SCHEMBL28775090 | 0.83 | PPARG (0.62) | PPARGPPARDPPARA | |
| SCHEMBL3525861 | 0.83 | PPARG (0.87) | PPARGPPARDPPARA | |
| SCHEMBL27713590 | 0.82 | PPARG (0.51) | PPARGPPARDPPARA | |
| SCHEMBL27733654 | 0.82 | PPARG (0.48) | PPARGPPARDPPARA | |
| SCHEMBL27713317 | 0.82 | PPARG (0.48) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |