Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK3 | P49761 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29732863 | 1.00 | CSNK2A1 (0.58) | CSNK2A1DYRK1AGSK3BALDH1A1MAPT | |
| SCHEMBL28775985 | 0.89 | MAPT (0.61) | CSNK2A1ALDH1A1MAPTFLT3POLB | |
| SCHEMBL29732649 | 0.89 | MAPT (0.61) | CSNK2A1ALDH1A1MAPTFLT3POLB | |
| SCHEMBL28776031 | 0.87 | FLT3 (0.69) | CSNK2A1DYRK1AGSK3BFLT3KMT2A | |
| SCHEMBL29732806 | 0.87 | FLT3 (0.69) | CSNK2A1DYRK1AGSK3BFLT3KMT2A | |
| SCHEMBL29732795 | 0.87 | DYRK1A (0.64) | CSNK2A1DYRK1AGSK3BFLT3MAP4K4 | |
| SCHEMBL28775983 | 0.87 | DYRK1A (0.64) | CSNK2A1DYRK1AGSK3BFLT3MAP4K4 | |
| SCHEMBL28776025 | 0.86 | GSK3B (0.52) | DYRK1AGSK3BALDH1A1MAPTOPRM1 | |
| SCHEMBL29733049 | 0.86 | GSK3B (0.52) | DYRK1AGSK3BALDH1A1MAPTOPRM1 | |
| SCHEMBL28775992 | 0.85 | DYRK1A (0.61) | DYRK1AGSK3BFLT3MAP4K4NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605329-B | Substituted indazole carboxamides or substituted azaindazole carboxamides FLT3 inhibitors and uses thereof | 河南中医药大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114605329-A | Substituted indazole carboxamide or substituted azaindazole carboxamide FLT3 inhibitors and uses thereof | 河南中医药大学 | 2022-06-10 | — | — | CN | disclosed |