Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28776244 | 1.00 | TDP1 (0.35) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27722012 | 0.92 | TDP1 (0.33) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27721978 | 0.92 | TDP1 (0.33) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27742732 | 0.92 | TDP1 (0.33) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28058841 | 0.88 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28058930 | 0.88 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28058842 | 0.88 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28095476 | 0.86 | TDP1 (0.35) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28055268 | 0.85 | TDP1 (0.34) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28055267 | 0.85 | TDP1 (0.34) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309918-B | [4-(benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-amine derivatives as ikk-beta inhibitors for the treatment of cancer and inflammatory diseases | LILLY CO ELI | 2010-12-29 | — | — | CN | disclosed |
| CN-101309918-A | [4-(benzo[b]thiophen-2-yl)-pyrimidin-2-yl]-amine derivatives as ikk-beta inhibitors for the treatment of cancer and inflammatory diseases | LILLY CO ELI (US) | 2008-11-19 | — | — | CN | disclosed |